Down syndrome occurs when an individual has an extra partial (or whole) copy of chromosome 21. It is not yet know why this syndrome occurs, but Down syndrome has always been a part of the human condition. It exists in all regions across the globe and commonly results in variable effects on learning styles, physical characteristics and health.

Adequate access to health care, to early intervention programmes, and to inclusive education, as well as appropriate research, are vital to the growth and development of the individual.

The message of With Us Not For Us is key to a human rights-based approach to disability.

We are committed to moving on from the outdated charity model of disability, where people with disability were treated as objects of charity, deserving of pity and relying on others for support.

A human rights-based approach views people with disabilities as having the right to be treated fairly and have the same opportunities as everyone else, working WITH others to improve their lives.